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A Textbook of In Vitro Fertilization and Assisted by Peter R. Brinsden

By Peter R. Brinsden

This significant e-book - often called 'The Bourn corridor Textbook' - advanced from instructing classes held at this prestigious medical institution - one of many birthplaces of IVF and scientific reproductive drugs. The content material is accomplished: overlaying overview of the infertile couple and either laboratory and scientific facets of assisted reproductive applied sciences. The emphasis all through is at the functional administration of sufferers present process assisted notion remedy. The 3rd variation is a whole replace of the sector together with increased sections on more moderen applied sciences akin to present and ICSI. The ebook is authored mostly via present or past participants of the Bourne corridor employees, with extra fabric from top foreign experts. The Bourn corridor strategies, Protocols and data Sheets - formerly released as an Appendix - are actually integrated on CD-ROM for ease of variation for neighborhood use.

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Extra info for A Textbook of In Vitro Fertilization and Assisted Reproduction: The Bourn Hall Guide to Clinical and Laboratory Practice

Example text

The gonadotropin-realising hormone agonist stimulation test – a sensitive predictor of performance in the flareup in vitro fertilization cycle. Fertil Steril 1990; 56: 711–17 74. Galtier-Dereure F, De Bouard V, Picot MC, et al. Ovarian reserve test with the gonadotropin-releasing hormone agonist buserelin: correlation with in vitro fertilization outcome. Hum Reprod 1996; 11: 1393–8 75. Lass A, Silye R, Abrams DC, et al. Follicular density in ovarian biopsy of infertile woman: a novel method to assess ovarian reserve.

The most comprehensive study was conducted on more than 50 000 cycles registered on the Human Fertilisation and Embryology Authority (HFEA) database136. Female age emerges as the single most important factor influencing the outcome of IVF136–139. The effect of increasing age on reduction in fertility has been discussed previously in this chapter. 5%) national observational study in the UK confirm this finding (Table 3). Biological age is more important than chronological age, as older women with a good response to superovulation and satisfactory cycles which result in embryos available for transfer have very reasonable chances of conceiving.

Increasing chronological age affects mainly implantation and pregnancy rates, whereas relatively young patients with elevated FSH levels have a higher chance of cycle cancelation due to poor response but fair to good implantation rates55. Age At Bourn Hall Clinic we check the day-2 FSH level in the treatment cycle of all patients of 38 years or older and women with previously reduced response to superovulation. Our cut-off point is 12 IU/ml, and if the level is above that threshold we postpone treatment and check the FSH again in the next cycle.

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